A resume is an important tool, but it can't get you a job. Only people can do that. If you want your job search to be successful, concentrate on people and prepare your resume to suit their needs.
Tailor both the resume and cover letter. How many times have you heard people say they customize their cover letter, but send the same resume to everyone? Usually they are very proud of themselves for doing this, as many job seekers send one form letter and resume to everyone. Unfortunately, when a resume is competing with 200 to 400 others, it has to stand out from the crowd. Recruiters don't have time to separate the "diamonds from the dirt" in the 10 to 60 seconds they spend skimming for relevant experience. It is the candidate's responsibility to sort the valuable stuff from the extraneous, using only 20-carat material to land an interview.
Have you ever tried to hire a new employee? While looking for a job is tough, finding a good employee is no picnic either. Picture yourself as the CEO of a small to midsize company looking for a new CFO. After carefully constructing your ad, you wade through scores of resumes, schedule and conduct several rounds of interviews, screen the princes from the frogs, and hope when you choose the best candidate, he will say yes. For a busy executive, this can be a long, expensive, and nerve-racking process with no guarantee of a positive result.