Despite conventional wisdom, you do not want to start your job search with a major resume effort. To do this puts the cart before the horse. A resume is really a kind of ad or brochure. Before developing an ad campaign, an advertising agency carefully targets its market and defines its customers' needs and priorities. Only after identifying these factors, does the copywriter describe features and benefits most useful to the targeted market. In your case, you are the product. You bear the responsibility of selling your most important experiences and attributes to potential employers on a person-to-person basis. If you write your resume before you have found out what they need, you are missing an opportunity to present your best case.
There is no universally preferred format. Many job seekers spend days perfecting their resumes, agonizing over whether to use a chronological format or a functional one. This question may be akin to figuring how many angels will fit on the head of a pin. There is no one perfect resume to suit every employer's needs. But there is a perfect resume for a specific opportunity. If you are going to focus on perfection, do it on an individual, rather than a global basis.
Employers don't consider your resume follow-up a waste of their time. While there will always be potential employers who are firm believers in the "don't call us, we'll call you" approach, most recruiters admire candidates who make an ef fort to follow up on their resumes. Follow-up shows both initiative and persistence, traits good managers love, especially in individuals who are applying for positions with major responsibilities. Don't worry about seeming too enthusiastic. Company representatives enjoy being pursued. It massages their egos and reminds them their company is worth courting.